Structure-Based Design of Tricyclic NF-κB Inducing Kinase (NIK) Inhibitors That Have High Selectivity over Phosphoinositide-3-kinase (PI3K) | Journal of Medicinal Chemistry
Frontiers | The Therapeutic Potential of Targeting NIK in B Cell Malignancies
Pharmacological inhibition of NF-κB-inducing kinase (NIK) with small molecules for the treatment of human diseases - RSC Medicinal Chemistry (RSC Publishing)
Cells | Free Full-Text | Inhibitory-κB Kinase (IKK) α and Nuclear Factor-κB (NFκB)-Inducing Kinase (NIK) as Anti-Cancer Drug Targets
IJMS | Free Full-Text | Targeting NF-κB-Inducing Kinase (NIK) in Immunity, Inflammation, and Cancer
The non-canonical NF-κB pathway in immunity and inflammation | Nature Reviews Immunology
NHRI researchers report expression of Nik-related kinase in smooth muscle cells attenuates vascular inflammation and intimal hyperplasia – NHRI Communications
Controlling the Fate of NIK: A Central Stage in Noncanonical NF-κB Signaling | Science Signaling
Targeting NF-κB pathway for the therapy of diseases: mechanism and clinical study | Signal Transduction and Targeted Therapy
IJMS | Free Full-Text | Targeting NF-κB-Inducing Kinase (NIK) in Immunity, Inflammation, and Cancer
NIK as a Druggable Mediator of Tissue Injury: Trends in Molecular Medicine
Functional interplay between NF-κB-inducing kinase and c-Abl kinases limits response to Aurora inhibitors in multiple myeloma | Haematologica
NF-κB inducing kinase (NIK) inhibitors: Identification of new scaffolds using virtual screening - ScienceDirect
Nik‐related kinase is targeted for proteasomal degradation by the chaperone‐dependent ubiquitin ligase CHIP - Naito - 2020 - FEBS Letters - Wiley Online Library
Pharmacological inhibition of NF-κB-inducing kinase (NIK) with small molecules for the treatment of human diseases - RSC Medicinal Chemistry (RSC Publishing) DOI:10.1039/D0MD00361A
Discovery of a Potent and Selective NF-κB-Inducing Kinase (NIK) Inhibitor That Has Anti-inflammatory Effects in Vitro and in Vivo | Journal of Medicinal Chemistry
Functional interplay between NF-κB-inducing kinase and c-Abl kinases limits response to Aurora inhibitors in multiple myeloma | Haematologica
NF-κB Inducing Kinase, NIK Mediates Cigarette Smoke/TNFα-Induced Histone Acetylation and Inflammation through Differential Activation of IKKs | PLOS ONE